Fig. 2
From: The suppressive effect of co-inhibiting PD-1 and CTLA-4 expression on H22 hepatomas in mice
IFN-γ, IL-10 and PD-L1 levels in the blood and tissue. These results are based on ELISA tests. CT = control, siPD-1 = group injected with siRNA for PD-1, siCTLA-4 = group injected with siRNA for CTLA-4, siPD-1 + siCTLA-4 = group injected with siRNA for PD-1 + CTLA-4. a – IFN-γlevel in mouse serum. b – IL-10 level in mouse serum. c – PD-L1 level in tumor tissue. d – PD-L1 content in liver tissue. The expressions of IFN-γ, IL-10 and PD-L1 in the blood and tissue of the siRNA groups were significantly different from those in the control group (**p < 0.01, *p < 0.05)