Fig. 1

MLO-Y4 cells responded to a mechanical tensile strain of 2500 microstrain (με) at 0.5 Hz for 8 h. a/b After MLO-Y4 cells were stimulated by the mechanical tensile strain, the contents of IGF-1 and PGE2 in the supernatant of cell culture medium were increased (n = 5). c The mechanical tensile strain increased protein levels of OPG (osteoprotegerin) of MLO-Y4 cells (n = 6). d Following mechanical tensile strain, the activities of NOS in the cells were up-regulated (n = 5). *P < 0.05 and **P < 0.01, compared with the unstrained control group