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Table 1 Predicted target genes of the miRs

From: miR-29b-3p regulated osteoblast differentiation via regulating IGF-1 secretion of mechanically stimulated osteocytes

miRNA

Annotation and Reference

RefseqID

mmu-miR-29b-3p

IGF-1, Insulin-like Growth Factor-1[23, 24]

NM_000076.6

Grip 1, Glutamate Receptor-Interacting Protein 1 [28]

NM_028736

Dtx4, deltex 4, E3 ubiquitin ligase [29]

NM_172442

Smad5, SMAD family member 5 [30]

NM_001164041

Wnt2b, wingless-type MMTV integration site family, member 2B [31]

NM_009520

Rptor, regulatory associated protein of MTOR complex 1 [32]

NM_028898

mmu-miR-361-3p

Map3k9, mitogen-activated protein kinase kinase kinase 9 [33]

NM_001174107

mmu-miR-713

Rag1, recombination activating gene 1 [34]

NM_009019

Gprc5a, G protein-coupled receptor, family C, group 5, member A [35]

NM_181444

mmu-miR-706

Dusp3, dual specificity phosphatase 3 [36]

NM_028207

Ncoa1, nuclear receptor coactivator 1[37]

NM_010881

Nkiras1, NFKB inhibitor interacting Ras-like protein 1[38]

NM_023526

mmu-miR-703

ZnT4, solute carrier family 30 [39]

NM_011774

Smad5, SMAD family member 5 [30]

NM_001164041

mmu-miR-574-3p

Tgfbr3, transforming growth factor, beta receptor III [40]

NM_011578

Dicer1, dicer 1, ribonuclease type III [41]

NM_148948

Pdk1, pyruvate dehydrogenase kinase, isoenzyme 1 [42]

NM_172665

mmu-miR-467b-3p

Runx2, runt-related protein 2 [43]

NM_001145920

Pdgfra, platelet derived growth factor receptor alpha [44]

NM_001083316

Mapk10, mitogen-activated protein kinase 10 [45]

NM_009158

mmu-miR-466i-5p

Atm, ataxia telangiectasia mutated [46]

NM_007499

Rgs2, regulator of G-protein signaling 2 [47]

NM_009061

Smo, smoothened, frizzled class receptor [48]

NM_176996

mmu-miR-466f-5p

Rcan1, regulator of calcineurin 1[49]

NM_001081549

Clock, circadian locomotor output cycles kaput [50]

NM_007715

Aff3, AF4/FMR2 family, member 3 [51]

NM_010678

mmu-miR-208a-3p

Il6ra, interleukin 6 receptor [52]

NM_010559

Acvr1c, activin A receptor type 1C [40]

NM_001111030

Sox6, SRY-Box 6 [40]

NM_011445

Sox5, SRY-Box 5 [40]

NM_011444

  1. For the target genes which are involved in bone formation, the references are provided