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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: MicroRNA-325-3p inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma by down-regulation of aquaporin 5

Fig. 4

Effects of miR-325-3p on cell proliferation and apoptosis in Huh7–1.3 and HepG2.2.15 cells. Huh7–1.3 and HepG2.2.15 cells were transfected with miR-325-3p mimic or miR-NC for 48 h. Cell proliferation was assessed by CCK-8 assay (a) and BrdU-ELISA assay (b). (c) Cell apoptosis was measured by nucleosomal degradation using Roche’s cell death ELISA detection kit. d Activities of caspase-3 were determined by caspase-3 activity detection assay. All data are presented as mean ± SEM, n = 6. #p < 0.05, ##p < 0.01 vs. miR-NC

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