Fig. 3

Honokiol inhibits serum inflammatory cytokines in septic mice. Serum levels of TNF-α (a), IL-6 (b) and IL-1β (c) were detected using mouse bioactive ELISA assay in CLP-induced septic mice. Values are expressed as mean ± SEM, n = 10 in Con or H + CLP group and n = 8 in CLP or L + CLP group. ^*** P < 0.001, versus control group; ^## P < 0.01 and ^### P < 0.001 versus CLP single treatment group