Concentration changes in gemcitabine and its metabolites after hyperthermia in pancreatic cancer cells assessed using RP-HPLC

Table 1 Absorbance and cell inhibition ratios of different concentrations of dFdC combined with hyperthermia as assessed with the MTT assay

Concentration (μg/ml)	Absorbance						Average value	SD	Inhibition ratio (%)
Concentration (μg/ml)	37 °C		41 °C		43 °C		Average value	SD	Inhibition ratio (%)
0	0.692	0.637	0.854	0.802	0.768	0.708	0.744	0.079
2.5	0.594	0.601	0.713	0.612	0.524	0.584	0.605	0.062	18.67
5.0	0.608	0.594	0.537	0.553	0.489	0.518	0.550	0.045	26.05
10.0	0.336	0.337	0.484	0.506	0.417	0.358	0.406	0.075	45.35
20.0	0.105	0.127	0.156	0.136	0.118	0.127	0.128	0.017	82.76
40.0	0.089	0.091	0.062	0.055	0.042	0.048	0.065	0.021	91.32

ISSN: 1689-1392