Fig. 4
From: MicroRNA-340-5p suppresses non-small cell lung cancer cell growth and metastasis by targeting ZNF503
Overexpression of ZNF503 reverses the inhibition of NCI-H1650 cell proliferation and invasion by miR-340-5p. a and b The mRNA (a) and protein (b) levels of ZNF503 in NCI-H1650 cells that were transfected with ZNF503 plasmids or vectors were respectively analyzed using qPCR or western blotting. c The data demonstrate relative protein expression. d The cell viability of miR-340-5p-overexpressing NCI-H1650 cells was partially elevated after overexpression of ZNF503. e Ectopic expression of ZNF503 facilitated cell invasion in NCI-H1650 cells that overexpress miR-340-5p. f The relative number of invasive cells is shown. Data are presented as the means ± SD (n = 3). *p < 0.05, **p < 0.01 and ***p < 0.001 versus the vector group or the scrambled group. #p < 0.05 versus the miR-340-5p mimic group