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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: Mesenchymal stem cells decrease blood–brain barrier permeability in rats with severe acute pancreatitis

Fig. 4

MSCs attenuated the downregulation of claudin-5 in the brains of SAP rats. a Immunohistochemistry staining of the brain (× 400). The immunohistochemistry staining shows that there is a higher expression of claudin-5 in BMECs in the control group than in the SAP group. The expression of claudin-5 in the SAP+MSCs group was higher than in the SAP group, although it was lower than in the control group. b Results of the quantitative real-time PCR assay of claudin-5 gene expression in the brains of SAP rats. c (i) Representative western blotting image of claudin-5 protein expression in the brains of SAP rats. (ii) Statistical analysis of claudin-5 protein expression based on a western blotting assay. *p < 0.05, **p < 0.01

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