Fig. 5
From: Dp71 depleted HBE cells displayed increased DNA damage and apoptosis induced by H2O2
Dp71 interacts with RAD51 in HBE cells. a Co-Ip revealed that RAD51 and lamin B1 were successfully pulled down by specific Dp71 antibody, while irrelevant IgG failed to pull down these two proteins. b Co-Ip revealed that Dp71 and lamin B1 were successfully pulled down by specific RAD51 antibody, while irrelevant IgG failed to pull down these two proteins. c Co-Ip revealed that Dp71 and RAD51 were successfully pulled down by specific lamin B1 antibody, while irrelevant IgG failed to pull down these two proteins. d Immunofluorescence displayed the co-localization of Dp71 and RAD51 in HBE cells (scale bar: 10 μm). e Significant reduction of Dp71 mRNA was observed in HBE-AS cells. f Significant reduction of RAD51 mRNA was observed in HBE-AS cells. g Significant reduction of lamin B1 mRNA was observed in HBE-AS cells. h Significant reduction of Dp71, RAD51 and lamin B1 protein was observed in HBE-AS cells