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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Long non-coding RNA Malat1 activated autophagy, hence promoting cell proliferation and inhibiting apoptosis by sponging miR-101 in colorectal cancer

Fig. 3

Malat1 increased cell proliferation and deduced apoptosis by activating autophagy. CCK-8 proliferation assay (a), flow cytometry (FCM) assay (b) and Western blot assay (c) show the effects of Malat1 downregulation or Malat1 upregulation on HCT116 and SW620 cell proliferation, apoptosis and apoptosis protein (cleaved caspase-3 and cleaved caspase-9) expression levels, and autophagy inhibition by 3-MA relieves induced cell proliferation and reduced cell apoptosis and cleaved caspase-3 expression level by Malat1 upregulation. The columns show the mean for three separate experiments. *p < 0.05, **p < 0.01

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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