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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2

Fig. 4

Costunolide suppresses the expression and activity of HK2 in HSCs. Primary rat HSCs at passages 3 through 5 were treated with costunolide at the indicated concentrations for 24 h. a – Real-time PCR for determining the mRNA expression of HK2. b – Western blot assay for determining the protein expression of HK2 with quantification of the blots. c – Measurement of the intracellular activity of HK2. Statistics: *p < 0.05, **p < 0.01 vs. control

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