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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Down-regulation of miR-30b-5p protects cardiomyocytes against hypoxia-induced injury by targeting Aven

Fig. 5

Knockdown of Aven partially reversed the protective effects of miR-30b-5p silencing. AC16 cells were co-transfected with miR-30b-5p inhibitor and siAven and then exposed to hypoxia for 12 h. a Protein expression levels of Aven were detected by Western blot analysis. Cell survival of cardiomyocytes was determined by MTT (b) and LDH (c) assays. d Cell apoptosis was evaluated by flow cytometry assay. *: inhibitor + si-NC vs. si-NC; #: inhibitor + siAven vs. inhibitor + si-NC; **p < 0.01, ***p < 0.001, ###p < 0.001

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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