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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: Upregulation of miR-376c-3p alleviates oxygen–glucose deprivation-induced cell injury by targeting ING5

Fig. 4

Knockdown of ING5 imitated the protective effect of miR-376c-3p against OGD-induced injury. PC-12 cells were transfected with si-ING5 or si-NC and then subjected to OGD. (a) The protein expression of ING5 was measured in PC-12 cells. (b) Cell viability was measured using the CCK-8 assay. (c) Cell cycle distribution was analyzed using flow cytometry with PI staining. (d) Cell apoptosis was examined using flow cytometry with Annexin V/PI double staining. *p < 0.05, **p < 0.01, ***p < 0.001 vs. si-NC

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