Fig. 5From: Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoterHypothetical schematic representation. E2 can upregulate the SREBP2 expression in hepatocytes via an ERE in the promoter. This induces elevated levels of cholesterol that may be related to increased risk of lipid disorder and cardiovascular disease. E2: estradiol; SREBP2: sterol regulatory element-binding protein; ERE: estrogen response elementBack to article page