Fig. 4From: MicroRNA-125b exerts antitumor functions in cutaneous squamous cell carcinoma by targeting the STAT3 pathwayKnockdown of STAT3 inhibits CSCC cell cycle progression or promotes cell apoptosis. a STAT3 knockdown by the miR-125b mimic and shRNA inhibits A431, SCC13 and SCL-1 cell cycle progression. b STAT3 knockdown by the miR-125b mimic or shRNA promotes A431, SCC13 and SCL-1 cell apoptosis. c Additional STAT3 supplementation can attenuate the apoptosis induced by the miR-125b mimic. Data are expressed as means ± SD of three independent experiments. *p < 0.05, compared with the miRNA scramble or shRNA controlBack to article page