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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: RETRACTED ARTICLE: Downregulation of miR-483-5p decreases hypoxia-induced injury in human cardiomyocytes by targeting MAPK3

Fig. 4

MiR-483-5p directly targets MAPK3 in AC16 cells subjected to hypoxia. a The predicted binding sites for miR-483-5p in the WT and MUT 3′-UTR of MAPK3. b Luciferase activity was measured using a luciferase reporter assay. Data are indicated as means ± SD of three independent experiments. **p < 0.01, as compared with miR-NC. c AC16 cells were transfected with miR-483-5p mimic or inhibitor, followed by 24 h hypoxia treatment. The protein level of MAPK3 was determined via western blot assay

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