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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: LncRNA CASC2 inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation and migration by regulating the miR-222/ING5 axis

Fig. 2

Overexpressed CASC2 suppresses hypoxia-induced PASMC proliferation and migration. PASMCs were transfected with CASC2 or si-CASC2 prior to exposure to hypoxia (3% O2) or normoxia for 24 h in triplicate. a, b Expression of CASC2 was detected by qRT-PCR in hypoxia- or normoxia-induced PASMCs. c, d Proliferation was determined using CCK-8 assay, and data were derived from an average of three independent experiments. e, f Wound healing assay was used to detect hypoxia-induced PASMC migration, and experiments were performed in triplicate. **P < 0.01, ***P < 0.001

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