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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: LncRNA CASC2 inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation and migration by regulating the miR-222/ING5 axis

Fig. 3

CASC2 is a sponge of miR-222. a Potential binding sites of miR-222 in CASC2 were predicted by bioinformatics analysis. b Enrichment of CASC2 and miR-222 was analyzed in PASMCs after Ago2 RIP. c Luciferase activity was measured in PASMCs co-transfected with CASC2-WT or CASC2-MUT and miR-NC, miR-222 or anti-miR-NC, anti-miR-222. d MiR-222 expression in PASMCs was examined after transfection with CASC2 or si-CASC2 using qRT-PCR, and results were presented as the average of three independent replicates. ***P < 0.001

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