Fig. 5
From: MiR-206 may suppress non-small lung cancer metastasis by targeting CORO1C
MiR-206 suppresses tumor growth of A549 xenograft mouse model. (a and b) MiR-206 inhibited A549 xenograft tumor growth. A549 cells suspended in PBS were injected subcutaneously into 5- to 6-week-old BABL/c (nu/nu) male mice to establish the xenograft. Then the mice were divided into the NC mimic group and miR-206 mimic group. The tumor volumes were measured by a slide caliper. At the end of the experiment, tumors were removed and frozen. The tumor volume curve and tumor weight are shown in a and b, respectively. c MiR-206 suppressed mRNA of EMT marker in tumor. Quantitative data are presented as mean ± SEM. ***P < 0.001 compared with the NC mimic group