Table 1 Mutations in Exon 1 of TCF-4 gene in Tumor Samples
From: TCF 4 tumor suppressor: a molecular target in the prognosis of sporadic colorectal cancer in humans
Sample | Fragment | Codon | Nucleotide altered | Predicted product |
|---|---|---|---|---|
S-2 | Exon 1 | 57 | AAC → ACA | Asparagine → Threonine |
S-2 | Exon 1 | 64 | GTA → TAG | Valine → STOP |
S-11 | Exon 1 | 56 | CCA → CAA | Glutamine → Glutamine |
S-11 | Exon 1 | 64 | GTA → TAG | Valine → STOP |
S-33 | Exon 1 | 22 | AAA → AAG | Lysine → Lysine |
S-33 | Exon 1 | 41 | TTA → TAG | Leucine → STOP |
S-34 | Exon 1 | 37 | GCA → GCG | Alanine → Alanine |
S-34 | Exon 1 | 41 | TTA → TAG | Leucine → STOP |
S-34 | Exon 1 | 48 | CTA → TAG | Leucine → STOP |
S-50 | Exon 1 | 33 | GAA → GAA | Glutamic Acid→Glutamic Acid |
S-50 | Exon 1 | 41 | TTA → TAG | Leucine → STOP |
S-50 | Exon 1 | 48 | CTA → TAG | Leucine → STOP |
S-50 | Exon 1 | 64 | GTA → TAG | Valine → STOP |