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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Targeting the 4-1BB costimulatory molecule through single chain antibodies promotes the human T-cell response

Fig. 3

The effects anti-4-1BB scFvs on the expression of the T-cell activation marker CD69. T cells were cultured at 106 cells/well in a 24-well plate, activated with anti-4-1BB scFvs and analyzed for CD69 expression using anti-CD69 PE antibody. The expression level of CD69 increased on T cells activated with PI.12, PI.42, PII.16 and PII.29 scFvs, but not with ES1 control scFv. These results are representative of at least three independent experiments. Dotted line histograms indicate untreated control T cells and gray filled histograms indicate T cells treated with anti-4-1BB and ES1 scFvs

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