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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: MicroRNA-186-5p serves as a diagnostic biomarker in atherosclerosis and regulates vascular smooth muscle cell proliferation and migration

Fig. 4

The effect of miR-186-5p on VSMC proliferation and migration. a Transfection with miR-186-5p mimics successfully and significantly increased the expression of miR-186-5p. Transfection with miR-186-5p inhibitors successfully and significantly decreased the expression of miR-186-5p. b Overexpression of miR-186-5p significantly promoted cell proliferation, while its downregulation yielded the opposite results. c The number of migrated cells increased significantly after overexpression of miR-186-5p and decreased after its downregulation. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the untreated group

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