Fig. 2

The effects of miR-637 on proliferation, migration and apoptosis of VSMCs. a – MiR-637 mimics were successfully transfected into VSMCs and VSMCs treated with 100 mg/l ox-LDL for 24 h. b – The migration of VSMCs was tested using a Transwell assay after transfection with miR-637 mimics. c – A CCK-8 assay was used to determine the effect of transfection with miR-637 mimics on the proliferation of VSMCs. d – The apoptosis rate of VSMCs was determined after transfection with miR-637 mimics. e – MiR-637 inhibitors were successfully transfected into VSMCs and VSMCs treated with 100 mg/l ox-LDL for 24 h. f – The migration of VSMCs was tested using a Transwell assay after transfection with miR-637 inhibitors. g – A CCK8 assay was used to determine the effect of transfection with miR-637 inhibitors on the proliferation of VSMCs. h – The apoptosis rate of VSMCs was determined after transfection with miR-637 inhibitors. *, ** and *** respectively indicate p < 0.05, p < 0.01 and p < 0.001. In Fig. C, * indicates p < 0.5, NC group VS miR-637 mimics group; ^& indicates p < 0.5, ox-LDL group VS ox-LDL + miR-637 mimics group; ^### indicates p < 0.001, NC group VS ox-LDL group. In Fig. G, * indicates p < 0.05, NC group VS miR-637 inhibitor group; ^& indicates p < 0.05, ox-LDL group VS ox-LDL + miR-637 inhibitor group; ^### indicates p < 0.001, ox-LDL group VS NC group