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Fig. 8 | Cellular & Molecular Biology Letters

Fig. 8

From: Knockdown of LINC00665 inhibits proliferation and invasion of breast cancer via competitive binding of miR-3619-5p and inhibition of catenin beta 1

Fig. 8

Effect of LINC00665/miR-3619-5p expression on β-catenin expression in breast cancer (BC) cells. a Potential binding sites between CTNNB1 and miR-3619-5p. b Luciferase reporter assay showing that the CTNNB1 3′-untranslated region has a direct binding site for miR-3619-5p. c Western blot showing LINC00665 knockdown and that miR-3619-5p overexpression inhibited expression of β catenin (encoded by CTNNB1). Simultaneous knockdown of LINC00665 and miR-3619-5p promoted β-catenin expression in MCF-7 and MDA-MB-231 cells

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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