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Table 1 Studies on arsenic trioxide-induced glioma cell death

From: Arsenic trioxide as a novel anti-glioma drug: a review

First author Cell line Does (μM) Time Findings Refs
Kanzawa U373, U87MG, U251, GB1, A-172, T98G 1,2,4 72 h Autophagy [19, 20]
Eun Hee Kim U373MG, U87MG, U251MG, U343, U251N, T98G 4,5,6 24 h No apoptosis [30]
Ye Cheng U87MG, U251, SHG44, C6 2,4,8 48 h Apoptosis [17]
Naomi Haga A172, T98G 1,10,50 48 h A172: apoptosis; T98G: no apoptosis [40]
Yuanyuan Sun C6, 9L 0.5–8 24,48,72 h Apoptosis [41]
Primon, M U87MG 2,5,10,20 72 h 2 μM:autophagy; More than 10 μM: apoptosis [21]
Karsy, M U87MG 0.5,1,2,4,16 24 h More than 4 μM: apoptosis [23]
Majid Zaki Dizaji U87MG 1,2 48 h Apoptosis [63]
G.-B. WANG U87MG 4,6,8 72 h Apoptosis [24]
Shiguang Zhao U87MG,T98G 1,2,4,8 12,24,48 h Apoptosis, the effect of T98 is greater than U87 [28]
Hui-Wen Chiu U118MG 2,4,6,8 12,18,24,36 h Autophagy and apoptosis [25]
Tain-Junn Cheng U118 1,5,10,25,50 24 h Autophagy [24]
Hui-Wen Chiu U118-MG 2 24 h Autophagy [27]
Yuanyan Wei SHG44 2,4,6 24 h Apoptosis [36]