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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: MicroRNA-296-5p inhibits cell metastasis and invasion in nasopharyngeal carcinoma by reversing transforming growth factor-β-induced epithelial–mesenchymal transition

Fig. 5

TGF-β overexpression rescues the miR-296-5p-induced inhibition of tumor metastasis in NPC cells via EMT. a Transwell assays showed that exogenous TGF-β rescued the miR-296-5p-induced inhibition of metastasis in NPC cells. Scale bar 100 µm. b Immunofluorescence showed exogenous TGF-β rescued the miR-296-5p-induced transition to epithelial-like cells. Scale bar 100 µm. c Western blotting confirmed exogenous TGF-β rescued the expression of the EMT-related proteins in NPC cells. d The relative expression levels of the EMT-related marker gene proteins with gray-scale analysis. *p < 0.05)

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