Fig. 8

Curcumin pre-treatment reduces iron overload-induced autophagy in bone marrow mononuclear cells in vitro. a—The effects of curcumin pre-treatment on mROS production. b, c—A representative immunoblot analysis of SIRT3 and SOD2 protein (b) and SOD2 acetylation (c). d—The effects of curcumin pre-treatment on SIRT3 activity. The values are presented as the means ± SEM, **p < 0.05 vs. the control group, ^##p < 0.05 vs. the FAC group