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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: Deficiency of αII-spectrin affects endothelial cell–matrix contact and migration leading to impairment of angiogenesis in vitro

Fig. 4

Spectrin depletion modifies focal points in endothelial cells. Focal points were analyzed using monoclonal antibodies directed against vinculin (red) and polyclonal antibodies directed against αII-spectrin (green) on HMEC-1 cells and HUVECs 72 h after transfection with Sp siRNA or Nr siRNA. Spectrin-depleted cells exhibited a reduced number of focal points compared to Nr siRNA-treated cells. Scale bar = 20 μm

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