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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: LINC00511 promotes proliferation and invasion by sponging miR-515-5p in gastric cancer

Fig. 4

MiR-515-5p is a target of LINC00511 in gastric cancer. a The recognized binding sites between LINC00511 and miR-515-5p. b MiR-515-5p expression in 25 pairs of gastric cancer tissues (GC tissues) was evaluated using quantitative RT-PCR. c Low miR-515-5p levels correlated with poor survival in gastric cancer patients based on the TCGA dataset. d MiR-515-5p overexpression led to a reduction in luciferase activity in the LINC00511-Wt group. e LINC00511 knockdown increased miR-515-5p expression in BGC823 cells. f The RIP assay revealed that both LINC00511 and miR-515-5p expression are enhanced in the mixture immunoprecipitated by anti-Ago2. g LINC00511 expression negatively correlated with miR-515-5p expression in gastric cancer tissues. *p < 0.05

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