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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy

Fig. 5

The molecular mechanism of ferroptosis and its relationship with MAFLD. The Fenton reaction and lipoxygenase regulation of ferroptosis via three regulatory pathways. Inhibition of the xc-system leads to depletion of GSH and excessive iron deposition through the Fenton reaction, causing lipid peroxidation and further leading to the progression of MAFLD

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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