Table 1 Genetic association models and disease risk
Model | Genotypes | Controls | Patients | Adjusted OR (95% CI) | P-value |
|---|---|---|---|---|---|
Codominant | G/G | 56 (53.9%) | 51 (46.4%) | 1.00 | 0.044 |
|  | A/G | 42 (40.4%) | 41 (37.3%) | 1.07 (0.60–1.90) |  |
|  | A/A | 6 (5.8%) | 18 (16.4%) | 3.27 (1.20–8.88) |  |
Dominant | G/G | 56 (53.9%) | 51 (46.4%) | 1.00 | 0.28 |
|  | A/G–A/A | 48 (46.1%) | 59 (53.6%) | 1.35 (0.79–2.30) |  |
Recessive | G/G–A/G | 98 (94.2%) | 92 (83.6%) | 1.00 | 0.013 |
|  | A/A | 6 (5.8%) | 18 (16.4%) | 3.17 (1.20–8.34) |  |
Over-dominant | G/G–A/A | 62 (59.6%) | 69 (62.7%) | 1.00 | 0.64 |
|  | A/G | 42 (40.4%) | 41 (37.3%) | 0.88 (0.51–1.52) |  |
Log-additive | – | – | – | 1.48 (0.99–2.22) | 0.053 |