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Table 3 CDKN2AB-AS1 quantification in cancer patients as a diagnostic and prognostic biomarker.

From: Association of cyclin-dependent kinase inhibitor 2B antisense RNA 1 gene expression and rs2383207 variant with breast cancer risk and survival

Cancer type

Methods

Expression pattern

PubMed ID

Circulatory diagnostic biomarker

 Breast cancer

Microarray, qPCR

Up-regulated

28248879

 Intraductal Papillary Mucinous Neoplasms of the Pancreas

qPCR

Up-regulated

28874676

 Acute lymphoblastic leukemia

MassARRAY assay

Up-regulated

21414664

 Neurofibromatosis type 1

Microarray, qPCR

Up-regulated

22034633

 Non-small cell lung cancer

qPCR

Up-regulated

29504701

 Oral cancer

qPCR, a Luciferase reporter assay, in vitro knockdown

Up-regulated

29635126

Prognostic biomarker

 Breast cancer

Microarray, qPCR

Up-regulated

28248879

 Triple-negative breast cancer

qPCR, Luciferase reporter assay, RIP

Up-regulated

28961506

 Non-small cell lung cancer

qPCR

Up-regulated

29504701

 Oral cancer

qPCR, a Luciferase reporter assay, in vitro knockdown

Up-regulated

29635126

 Gastric cancer

qPCR, RNAi

Up-regulated

27121324

 Lung adenocarcinoma

qPCR, Western blot

Up-regulated

28402932

 Bladder cancer

qPCR, RNAi, Western blot

Up-regulated

26800519

 Cervical cancer

qPCR, RNAi, Western blot, Cell proliferation assay

Up-regulated

27899255

 Colorectal cancer

qPCR, RNAi, Western blot, Northern blot

Up-regulated

27286457

 Colorectal cancer

qPCR, RNAi

Up-regulated

27314206

 Esophageal squamous cell cancer

qPCR, RNAi, Western blot

Up-regulated

24747824

 Gallbladder cancer

qPCR, Western blot

Down-regulated

26812694

 Gastric cancer

qPCR, RNAi, Western blot, RIP

Up-regulated

24810364

 Gastric cancer

qPCR, RNAi, Western blot, a Luciferase reporter assay, Cell proliferation assay

Up-regulated

27027260

 Glioblastoma

qPCR

Up-regulated

23046790

 Hepatocellular carcinoma

qPCR, Western blot

Up-regulated

29029488

 Hepatocellular carcinoma

qPCR, RNAi

Up-regulated

26045820

 Lung cancer

qPCR, RNAi, Western blot, Cell apoptosis assay

Up-regulated

25964559

 Nasopharyngeal cancer

RT-qPCR, Western blot, a Luciferase reporter assay, in vitro knockdown, RIP

Up-regulated

29463902

 Nasopharyngeal cancer

qPCR, RNAi, Western blot, MTT assay

Up-regulated

27557514

 Non-small cell lung cancer

qPCR, RNAi, Western blot, Luciferase reporter assay

Up-regulated

27307748

 Non-small cell lung cancer

qPCR, RNAi, Cell proliferation assay

Up-regulated

25889788

 Non-small cell lung cancer

qPCR, Western blot

Up-regulated

25504755

 Osteosarcoma

qRT-PCR, Western blot, in vitro knockdown

Up-regulated

29520337

 Ovarian cancer

qPCR, Western blot

Up-regulated

27095571

 Pancreatic cancer

qPCR, Cell transfection, Western blot, cell migration, and invasion assay

Up-regulated

28344092

 Renal cell carcinoma

qPCR, RNAi, Western blot, Cell migration and invasion assay, CCK-8 assay

Up-regulated

28251886

 Serous ovarian cancer

qPCR, RNAi, Western blot

Up-regulated

25845387

 Thyroid cancer

qPCR, RNAi, Western blot

Up-regulated

27507052

  1. Breast cancer-related articles are shown in bold