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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Worenine reverses the Warburg effect and inhibits colon cancer cell growth by negatively regulating HIF-1α

Fig. 3

Key glycolytic enzymes are inhibited by worenine. HCT116 cells were treated with 5, 10 or 20 μM worenine for 24 h. a The protein expressions of GLUT3, HK2, PKM2 and LDHA were determined using western blotting. b he results for the quantitative RT-PCR analysis of the mRNA expressions of GLUT3, HK2, PKM2 and LDHA in worenine-treated cells. c HK-2 and PFK-1 expression were evaluated using immunofluorescence. Cells were co-stained with DAPI to visualize the nuclei. The data are means ± SEM. #p < 0.05, ##p < 0.01 vs. control group

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