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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: LncRNA TP73-AS1 promotes oxidized low-density lipoprotein-induced apoptosis of endothelial cells in atherosclerosis by targeting the miR-654-3p/AKT3 axis

Fig. 7

MiR-654-3p mimics inhibited apoptosis of ox-LDL treated HAECs through targeting AKT3. A AKT3 level evaluated by qRT-PCR in HAECs transfected with pc-AKT3 or pc-NC, and treated with ox-LDL for 24 h. B–D (B) Cell viability assessed by CCK-8 assay, C apoptosis evaluated by flow cytometry and D the levels of apoptosis-related proteins detected by Western blot in HAECs transfected with miR-NC, miR-654-3p mimics, pc-AKT3, or co-transfected with miR-654-3p mimics and pc-AKT3, and treated with ox-LDL for 24 h. * P < 0.05, ** P < 0.01

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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