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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Tumor suppressive role of miR-33a-5p in pancreatic ductal adenocarcinoma cells by directly targeting RAP2A

Fig. 2

MiR-33a-5p exerted suppressive effects on PDAC cell proliferation, migration and invasion. A Expression level of miR-33a-5p was assessed by RT-qPCR in SW1990 and PANC-1 cells after transection with the miR-33a-5p mimics or miR-NC. B CCK-8 assay was used to evaluate changes in SW1990 and PANC-1 cell proliferation following transfection with miR-33a-5p mimics or miR-NC. C, D Cell migration and invasion were analyzed in SW1990 and PANC-1 cells following transfection with miR-33a-5p mimics or miR-NC. E BxPC-3 and ASPC-1 cells were transected with the miR-33a-5p inhibitor or miR-NC. After that, the expression level of miR-33a-5p was assessed by RT-qPCR. F Changes in proliferation of transfected BxPC-3 and ASPC-1 cells were evaluated by the CCK-8 assay. G, H Cell migration and invasion were analyzed in transfected BxPC-3 and ASPC-1. **p < 0.01, ***p < 0.001 vs. miR-NC or inhibitor NC group

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