Fig. 2
From: MiR-501 promotes tumor proliferation and metastasis by targeting HOXD10 in endometrial cancer
MiR-501 promotes proliferation of endometrial cancer cells. A (i) Overexpression of miR-501 promotes cell growth in endometrial cancer cells. (ii) Downregulation of miR-501 inhibited proliferation of endometrial cancer cells. B Overexpression of miR-501 could promote colony formation ability in AN3 CA (i) and Ishikawa cell lines (ii). C (i, ii) Overexpression of miR-501 can promote the cell cycle into G2 phase. (iii) Upregulated miR-501 can inhibit the expression of p21. D, In nude mice xenograft models, the tumor volume and weight of the miR-501 up-regulated groups were significantly higher than in the control. *p < 0.05, **p < 0.01, ***p < 0.001