Fig. 6

UCA1 acts as a sponge of miR-145 in GC. A Putative binding site of miR-145 on UCA1. The red nucleotides were the seed sequences of miR-145 and the blue nucleotides were deleted in the MUT-UCA1. B Dual-luciferase reporter assays of GC cells co-transfected with WT/MUT UCA1 and miR-145 mimics or miR-NC. C RIP assay showed that both UCA1 and miR-145 existed in the production precipitated by anti-AGO2. D miR-145 expression levels in GC tissues and normal tissues. E miR-145 expression levels in GC cell lines. F. Knockdown of UCA1 increased the expression level of miR-145 IN GC cell lines. *p < 0.05, **p < 0.01, compared with control cells