Fig. 9

UCA1 reverses the effect of the miR-145/MYO6 axis on GC cell proliferation and apoptosis. A CCK-8 assay showed that pcDNA3.1-UCA1 partially reversed the repression effect of miR-145 mimics or siMYO6 on BGC-823 cell proliferation. B CCK-8 assay showed that pcDNA3.1-UCA1 partially reversed the repression effect of miR-145 mimics or siMYO6 on MGC-803 cell proliferation. C Flow cytometry assay showed that the increased apoptosis induced by miR-145 mimics or siMYO6 in BGC-823 cell lines was suppressed by pcDNA3.1-UCA1 co-transfection. D Flow cytometry assay showed that the increased apoptosis induced by miR-145 mimics or siMYO6 in MGC-803 cell lines was suppressed by pcDNA3.1-UCA1 co-transfection. E Western blot results showing MYO6 expression in BGC-823 and MGC-803 cells after siMYO6, miR-145 mimics, or pcDNA3.1-UCA1 transfection. *p < 0.05, compared with control cells