Fig. 4
From: MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer
Silencing of MYCBP inhibited TNBC cell proliferation, migration and invasion. Transfection efficiency of si-MYCBP#1 or si-MYCBP#2 in MDA-MB-468 and BT-549 cells was detected by PCR assay (A) and western blot analysis (B). C CCK-8 assay was used to determine the cell viability of MDA-MB-468 and BT-549 cells after transfection with si-MYCBP#1, si-MYCBP#2 or si-NC. D The influence of MYCBP knockdown on cell proliferation of MDA-MB-468 and BT-549 cells was detected by colony formation assay. MYCBP knockdown decreased the number of migrated (E) and invasive (F) cells. Magnification, ×200; scale bar, 100 μm; data are shown as mean ± SD (n = 3). *p < 0.05, **p < 0.01 and ***p < 0.001 compared with si-NC group