Fig. 2

Cancer-associated alteration in TP53 and MDM2. The distribution of alterations in TP53 and MDM2 genes divided by cancer type (colour coding: deep red = amplification, green = structural variation, yellow = deep deletion, red = mutation, dark blue = multiple alterations). The cancer types are ordered from lowest to highest percent of TP53 alterations. The data were obtained from TCGA [83]