Fig. 1

Acacetin restrained ovarian cancer cell malignancy. A Chemical structure of acacetin. B Normal human ovarian surface epithelial cell line IOSE80 was treated with the indicated doses of acacetin for 24 h; cell viability was then analyzed. C Human SKOV3 ovarian cancer cells were treated with various doses of acacetin (1–20 µM) for 24 and 48 h. Then, cell viability was determined by MTT assay. D After treatment with the indicated dose for 48 h, annexin V-FITC/PI staining was carried out to evaluate cell apoptosis. E Cell invasion was assessed by Transwell assay. *P < 0.05 vs. control group