Fig. 2

Administration with acacetin offset conditioned medium-induced ovarian cancer cell growth and invasion. A Ovarian cancer cells were incubated with conditioned medium (CM) from peritoneal mesothelial cells in presence of the indicated doses of acacetin. Approximately 48 h later, cell viability was detected by MTT assay. B The protein expression of proliferation-related PCNA was analyzed by western blotting. C, D Transwell assay was performed to evaluate cell invasion. E, F The corresponding effects on protein expression of MMP-2 and MMP-9. *P < 0.05