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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Peptidylarginine deiminase 2 promotes T helper 17-like T cell activation and activated T cell-autonomous death (ACAD) through an endoplasmic reticulum stress and autophagy coupling mechanism

Fig. 1

Induction of autophagy and apoptosis in T-ALL cell lines, Jurkat T, DND-41, and P12-ICHIKAWA by TPA and ionomycin (Ion). A The bar graphs derived from acridine orange (AO) staining images of Jurkat T, DND-41, and P12-ICHIKAWA cells (Additional file 1: Fig. S1A) show the percentages of the cell with autophagosomes or apoptotic bodies. The data are presented as the mean ± SEM of three separate experiments (*p < 0.05, **p < 0.01, and ***p < 0.001). The p value in was calculated by one-way ANOVA. B Proteins extracted from Jurkat T, DND-41, and P12-ICHIKAWA cells were detected using antibodies against PADI2 and β-actin. The value indicates the ratio of protein signal to β-actin signal.

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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