Fig. 5

Effects of the ferroptosis inhibitor on lipopolysaccharide (LPS)-induced acute lung injury (ALI). A Representative images of the mouse lung tissues. B Representative terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) fluorescence images of the lung tissues. C Representative immunohistochemistry-based images of GPX4 and 4-HNE in the lung tissues. D Lung wet weight/dry (W/D) weight ratio. E–G Concentrations of IL-1β, IL-6, and TNF-α in bronchoalveolar lavage fluid (BALF). Similar results were obtained from three independent experiments. All data are presented as mean ± SEM (n = 6 for each group). ^#/*P < 0.05, ^##/**P < 0.01, ^###/***P < 0.001, ^# versus control group; * versus LPS group