Fig. 5From: RETRACTED ARTICLE:Parecoxib inhibits esophageal squamous cell carcinoma progression via the PDK1–AKT pathwayGraphic abstract. Parecoxib regulated cell cycle, proliferation, invasion, and migration via the PDK1–AKT signaling pathway. Specifically, parecoxib induced cell cycle arrest at G2 via PDK1/AKT/mutant p53/p21waf1, and inhibited ECM degradation so as to suppress ESCC invasion and migrationBack to article page