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Table 5 Functional annotation of PDEmRNAs in co-expression network

From: Identification and validation of an eight-lncRNA signature that predicts prognosis in patients with esophageal squamous cell carcinoma

Category Term Gene count p-Value FDR
Biology process Keratinocyte differentiation (GO:0030216) 9 6.81 × 10−12 1.72 × 10−9
  Epidermal cell differentiation (GO:0009913) 8 7.94 × 10−10 1.00 × 10−7
  Peptide cross-linking (GO:0018149) 7 2.02 × 10−9 1.70 × 10−7
  Epidermis development (GO:0008544) 8 3.63 × 10−9 2.29 × 10−7
  Epithelial cell development (GO:0002064) 3 5.92 × 10−5 2.49 × 10−3
  Insulin metabolic process (GO:1901142) 2 7.22 × 10−4 2.03 × 10−2
  Regulation of T-helper-2 cell differentiation (GO:0045628) 2 7.22 × 10−4 2.03 × 10−2
  Negative regulation of endopeptidase activity (GO:0010951) 4 5.86 × 10−4 2.03 × 10−2
  Epithelial cell morphogenesis (GO:0003382) 2 1.10 × 10−3 2.77 × 10−2
  Positive regulation of T-helper cell differentiation (GO:0045624) 2 1.31 × 10−3 3.01 × 10−2
  Regulation of exocytosis (GO:0017157) 3 1.71 × 10−3 3.61 × 10−2
  Monocarboxylic acid transport (GO:0015718) 3 1.91 × 10−3 3.71 × 10−2
  Fibrinolysis (GO:0042730) 2 2.66 × 10−3 4.72 × 10−2
KEGG pathway Regulation of tissue remodeling (GO:0034103) 2 2.99 × 10−3 4.72 × 10−2
  Negative regulation of peptidase activity (GO:0010466) 3 2.97 × 10−3 4.72 × 10−2
  Bile secretion 3 5.35 × 10−5 4.33 × 10−3
  Salivary secretion 3 9.94 × 10−5 8.05 × 10−3
  Complement and coagulation cascades 2 5.56 × 10−4 4.50 × 10−2