Table 5 Functional annotation of PDEmRNAs in co-expression network
Category | Term | Gene count | p-Value | FDR |
|---|---|---|---|---|
Biology process | Keratinocyte differentiation (GO:0030216) | 9 | 6.81 × 10−12 | 1.72 × 10−9 |
|  | Epidermal cell differentiation (GO:0009913) | 8 | 7.94 × 10−10 | 1.00 × 10−7 |
|  | Peptide cross-linking (GO:0018149) | 7 | 2.02 × 10−9 | 1.70 × 10−7 |
|  | Epidermis development (GO:0008544) | 8 | 3.63 × 10−9 | 2.29 × 10−7 |
|  | Epithelial cell development (GO:0002064) | 3 | 5.92 × 10−5 | 2.49 × 10−3 |
|  | Insulin metabolic process (GO:1901142) | 2 | 7.22 × 10−4 | 2.03 × 10−2 |
|  | Regulation of T-helper-2 cell differentiation (GO:0045628) | 2 | 7.22 × 10−4 | 2.03 × 10−2 |
|  | Negative regulation of endopeptidase activity (GO:0010951) | 4 | 5.86 × 10−4 | 2.03 × 10−2 |
|  | Epithelial cell morphogenesis (GO:0003382) | 2 | 1.10 × 10−3 | 2.77 × 10−2 |
|  | Positive regulation of T-helper cell differentiation (GO:0045624) | 2 | 1.31 × 10−3 | 3.01 × 10−2 |
|  | Regulation of exocytosis (GO:0017157) | 3 | 1.71 × 10−3 | 3.61 × 10−2 |
|  | Monocarboxylic acid transport (GO:0015718) | 3 | 1.91 × 10−3 | 3.71 × 10−2 |
|  | Fibrinolysis (GO:0042730) | 2 | 2.66 × 10−3 | 4.72 × 10−2 |
KEGG pathway | Regulation of tissue remodeling (GO:0034103) | 2 | 2.99 × 10−3 | 4.72 × 10−2 |
|  | Negative regulation of peptidase activity (GO:0010466) | 3 | 2.97 × 10−3 | 4.72 × 10−2 |
|  | Bile secretion | 3 | 5.35 × 10−5 | 4.33 × 10−3 |
|  | Salivary secretion | 3 | 9.94 × 10−5 | 8.05 × 10−3 |
|  | Complement and coagulation cascades | 2 | 5.56 × 10−4 | 4.50 × 10−2 |