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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: HCMV-miR-US33-5p promotes apoptosis of aortic vascular smooth muscle cells by targeting EPAS1/SLC3A2 pathway

Fig. 3

HCMV-miR-US33-5p inhibits key factors of integrin signaling pathway in HA-VSMCs. A Volcano plot for DEGs in the control (n = 3) and HCMV-miR-US33-5p transfection (n = 3) groups. Green and red points represent genes downregulated and upregulated in the HCMV-miR-US33-5p transfection group, respectively. B Heatmap for DEGs in the control (n = 3) and HCMV-miR-US33-5p transfection (n = 3) groups. C GO annotations; D KEGG enrichment analysis. E–H Western blot analysis of p-FAK (E), p-AKT (F), pY20 CAS (G), and GTP-Rac (H) in HA-VSMCs. Western blot was performed three times; representative images are presented. Numbers above lanes indicate the relative protein level, normalized relative to the control samples

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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