Table 2 Combined therapies of hydroxychloroquine with other drugs tested for COVID-19 treatment

Hydroxychloroquine + favipiravir

Clinical benefits not observed

[99]

Hydroxychloroquine + azithromycin

Clinical benefits not observed

[100, 101]

Hydroxychloroquine + omega-3

Patients receiving omega-3 indicated favorable changes in all clinical symptoms except for olfactory

[102]

Hydroxychloroquine + ribavirin

Clinical benefits not observed

[103]

Hydroxychloroquine + zinc

Zinc supplements did not enhance the clinical efficacy of hydroxychloroquine

[104]