Skip to main content
Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Molecular mechanism of lncRNA SNHG12 in immune escape of non-small cell lung cancer through the HuR/PD-L1/USP8 axis

Fig. 3

lncRNA SNHG12 downregulation blocked the immune escape of NSCLC. A549 or H1299 cells in different treatment groups were co-cultured with isolated PBMCs. A PBMC proliferation was observed via Ki67 staining; B percentage of CD8+ T cells in PBMCs was determined via flow cytometry; C concentrations of TNF-α, IFN-γ, IL-10, and TGF-β were determined via ELISA; D cytotoxicity of PBMCs was detected via LDH cytotoxicity assay. Cell experiments were performed in triplicates, *P < 0.05, **P < 0.01. Data were represented as mean ± standard deviation. Multigroup comparisons in A, B, and D were analyzed using one-way ANOVA and in C were analyzed using two-way ANOVA, followed by Tukey’s multiple comparison test

Back to article page