Table 4 The function of miRNAs in different immune cells [129]
From: The role of epigenetic modifications in drug resistance and treatment of breast cancer
Function | miRNAs |
|---|---|
Inhibition of monocyte differentiation of maturation | miR-17-5p, miR-20a, miR-106a |
Activation of monocyte differentiation | miR-155, miR-21, miR-17-92, miR-424 |
M1 polarization | miR-21, miR-146a |
M2 polarization | miR-155, miR-125a/b |
Maturation and regulation function of NK | miR-155 |
Regulation of NK from CD34 +  | miR-181 |
Cytotoxicity of NK cells | miR-30e, miR-378, miR-27a-5p |
Regulation of the expression of PD-L1 | miR-34a-5p, miR-138-5p, miR-200, miR-424, miR-513 |
Regulation of the expression of PD-1 | miR-135-5p |
Regulation of CTLA-4 | miR-138-5p |